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Bretylium (Bretylol) =
CLASS:
ACTION:
Causes release =
of
norepinephrine from adrenergic nerve endings, which in turn causes sli=
ght
increase in heart rate, blood pressure, cardiac output
Then norepine=
phrine
release is inhibited which results in adrenergic blockade, then
hypotension may develop
Elevates ventri=
cular
threshold Sometimes conve=
rts
ventricular fibrillation or ventricular tachycardia to supraventricular
rhythms
INDICATIONS:
Ventricular
fibrillation/ventricular tachycardia refractory to Lidocaine
CONTRAINDICATIONS:
None in life
threatening ventricular arrhythmias
PRECAUTIONS:
Keep patient in
supine position due to possible hypotension
SIDE
EFFECTS:
Dizziness<=
/o:p> Syncope Seizures Hypertension Hypotension Projectile vomi=
ting Angina
DOSAGE/ROUTE:
5 mg/kg IV bolu=
s After 5 minutes=
, 10
mg/kg Max 30 mg/kg If rhythm conve=
rts,
use drip to maintain
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