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Heparin
CLASS:
Anticoagulant,
antithrombotic
ACTION:
Prevents conver=
sion
of fibrinogen to fibrin and prothrombin to thrombin by enhancing
inhibiting effects of antithrombin III
INDICATIONS:
Deep vein throm=
bus Pulmonary embol=
us MI Open heart surg=
ery
CONTRAINDICATIONS:
Hemophilia=
Leukemia Peptic ulcer di=
sease Severe hepatic =
or
renal disease Severe hyperten=
sion Hypersensitivit=
y
PRECAUTIONS:
Alcoholism=
Elderly Pregnancy<=
/o:p>
SIDE
EFFECTS:
Hepatitis<=
/o:p> Thrombocytopeni=
a Fever Diarrhea Anaphylaxis Hematuria<=
/o:p>
DOSAGE/ROUTE:
DVT/MI:
IV bolus 5000
– 7500 units, then IV infusion 1000 units/hr titrated to PTT le=
vel
PE:
IV bolus
7500-10,000 units, then IV infusion 1000 units/hr titrated to PTT lev=
el
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