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Isoproterenol (Isuprel)
CLASS:
ACTION:
Synthetic
catecholamine acts almost exclusively on Beta receptors; primarily on
heart and lungs due to no Alpha receptor stimulating capabilities=
Increases heart=
rate
in bradycardias that are refractory to Atropine
INDICATIONS:
Bradycardias
refractory to Atropine when pacing is unavailable
Bradycardias
resulting from high degree heart blocks Severe status
asthmaticus
CONTRAINDICATIONS:
Not used to inc=
rease
blood pressure in cardiogenic shock Should only be =
used
in shock resulting from bradycardias
PRECAUTIONS:
Monitor for PVC=
s, V
tach, and V fib In MI, can cause
myocardial ischemia
SIDE
EFFECTS:
Nervousness Tachycardia/pal=
pitations Angina Hypertension/hy=
potension Ventricular
arrhythmias Pulmonary edema=
DOSAGE/ROUTE:
2-20 mcg/min IV
infusion only (piggyback) 1 mg diluted in=
500
ml of D5W (concentration 2 mg/ml)
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