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Aminophylline (Somophyllin)
CLASS:
ACTION:
Relaxes bronchi=
al
smooth muscle but does not act on adrenergic receptors Stimulates
respiratory center in brain Mild diuretic
effects; increases heart rate and cardiac output; may precipitate
arrhythmias
INDICATIONS:
Bronchial asthm=
a Reversible
bronchospasm associated with chronic bronchitis and emphysema CHF, pulmonary =
edema
CONTRAINDICATIONS:
Patients with
uncontrolled cardiac dysrhythmias Hypersensitivit=
y
PRECAUTIONS:
History of
cardiovascular disease or hypertension Hypotension can=
occur
following rapid administration Monitor with ca=
rdiac
monitor and be alert for PVCs and tachycardia
SIDE
EFFECTS:
Tachycardia/arr=
hythmias/palpitations Chest pain=
Nervousness Headache Seizures
DOSAGE/ROUTE:
Non-CHF: =
250-500
mg in 100 ml NS and infused over 20-30 minutes CHF: &n=
bsp; 250-500
mg (2-5 mg/kg) in 20 ml and infused 20-30 minutes
SUPPLIED:
Ampule containi=
ng 250
mg in 10 ml solvent or containing 500 mg in 20 ml solvent
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