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Procainamide (Pronestyl)
CLASS:
ACTION:
Reduces automat=
icity
of various pacemaker sites in the heart Slow intraventr=
icular
conduction to a much greater degree than does Lidocaine Suppresses
ventricular ectopy
INDICATIONS:
Persistent card=
iac
arrest due to V Fib and refractory to Lidocaine PVCs refractory=
to
Lidocaine V Tach refracto=
ry to
Lidocaine
CONTRAINDICATIONS:
2nd =
and 3rd
degree heart blocks PVCs in conjunc=
tion
with bradycardia Myasthenia grav=
is
PRECAUTIONS:
Monitor BP cons=
tantly CHF/respiratory
depression
SIDE
EFFECTS:
Hypotension Seizures Respiratory/car=
diac
arrest Heart blocks Bradycardia
DOSAGE/ROUTE:
Bolus: 20-30 mg=
/min
slow IV bolus with max 17 mg/kg
1 gm in 50 ml
making a 20:1 concentration 20 mg/min =3D=
60
gtt/min 30 mg/min =3D=
90 gtt/min
Infusion: 1 gm =
in 250
ml making a 4:1 concentration Discontinue if:=
Arrhythmia is
suppressed Hypotension QRS widened b=
y 50% Total 17 mg/k=
g
SUPPLIED:
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