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Verapamil (Calan)
CLASS:
ACTION:
Vascular dilati=
on and
slows conduction through AV node Inhibits calciu=
m ion
influx across cell membrane during cardiac depolarization Decreases rapid
ventricular response seen with atrial tachydysrhythmias such as atrial
fibrillation and atrial flutter Decreases myoca=
rdial
demand Negative inotro=
pic
effects Coronary and
peripheral vasodilation
INDICATIONS:
PSVT refractory=
to
adenosine Atrial fibrilla=
tion
and atrial flutter
CONTRAINDICATIONS:
Severe hypotens=
ion Cardiogenic sho=
ck V Tach Wolff-Parkinson=
-White
syndrome Sick sinus synd=
rome Severe CHF
PRECAUTIONS:
Monitor BP cons=
tantly Hypotension Renal disease
SIDE
EFFECTS:
Hypotension Asystole Heart block Nausea/vomiting=
Bradycardia CHF Headache
DOSAGE/ROUTE:
2.5 - 5.0 mg IV=
push
over 2 minutes After 15-30 min=
utes,
5-10 mg IV Max dose: 30 mg=
in 30
minutes Antedote: Calcium chloride: 0.5 - 1.0 g=
m over
5 minutes slow IV push
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